null

SMILES COc1cccc2[C@H](CN(C)CCc3ccc4ccoc4c3)CCCc12

InChI Key InChIKey=MHPMXTGKTXJIDI-IBGZPJMESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50057128   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)copy SMILEScopy InChI
Affinity DataKi:  3.77nMAssay Description:Evaluated for affinity at 5-HT uptake site using [3H]paroxetine as radioligand in radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HZ0
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:In vitro binding affinity towards rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43SGCPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]- paroxetine binding to 5-HTT receptor, serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7MZCPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)copy SMILEScopy InChI
Affinity DataIC50: 13.1nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9P6WPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057128((2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-t...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WZ9PubMed