null
SMILES COc1cccc2[C@H](CN(C)CCc3ccc4ccoc4c3)CCCc12
InChI Key InChIKey=MHPMXTGKTXJIDI-IBGZPJMESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50057128
Affinity DataKi: 3.77nMAssay Description:Evaluated for affinity at 5-HT uptake site using [3H]paroxetine as radioligand in radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:In vitro binding affinity towards rat serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of [3H]- paroxetine binding to 5-HTT receptor, serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 13.1nMAssay Description:Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against serotonin transporterMore data for this Ligand-Target Pair