null

SMILES CNC(C)C1(CCCCC1)c1ccc2ccccc2c1

InChI Key InChIKey=WISXSHNMYCUZHH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50337912   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J2PPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 118nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J2PPubMed