null

SMILES CN(C(C)=O)C1(CCN(CCC[C@@]2(CCCN(C2)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1)c1ccccc1

InChI Key InChIKey=DZOJBGLFWINFBF-UMSFTDKQSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50291261   

TargetSubstance-K receptor(Rattus norvegicus (Rat))
SmithKline Beecham S.p.A.

Curated by ChEMBL
LigandPNGBDBM50291261((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...)copy SMILEScopy InChI
Affinity DataKi:  0.510nMAssay Description:Ability to displace [125I]NKA from Tachykinin receptor 2 in rat deodenum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6CJRPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50291261((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...)copy SMILEScopy InChI
Affinity DataKi:  35.5nMAssay Description:Displacement of [3H]SR48968 from human recombinant NK2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0MBPPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50291261((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Binding Affinity of [125I]NKA towards Tachykinin receptor 2-CHO cell membranes (n=3-8)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6CJRPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50291261((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...)copy SMILEScopy InChI
Affinity DataKi:  79nMAssay Description:Displacement of [125I]-neurokinin A from human NK2R after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP47TCPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50291261((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...)copy SMILEScopy InChI
Affinity DataKi:  85nMAssay Description:Binding affinity to human NK2 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed