null
SMILES COc1cc(cc(OC)c1OC)-c1cc(cnc1C)-c1ccc(cc1)N1CCNCC1
InChI Key InChIKey=BHUXVRVMMYAXKN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50056676
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute of Technology
Curated by ChEMBL
Massachusetts Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute of Technology
Curated by ChEMBL
Massachusetts Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293T cells cotransfected with CAGA reporter encoding luciferase by luciferase reporter ge...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute of Technology
Curated by ChEMBL
Massachusetts Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ALK5 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute of Technology
Curated by ChEMBL
Massachusetts Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair