null

SMILES F[C@H]1CNCC[C@@H]1n1cc2cc(cc(c2n1)C(F)(F)F)-c1ccc(=O)n2CCCc12

InChI Key InChIKey=WLDNDKUPNXWOSV-WMZOPIPTSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50543142   

TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50543142(CHEMBL4641633)copy SMILEScopy InChI
Affinity DataIC50: 0.620nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of DOTAP-ssRNA40 induced IFNalpha production preincubated for 30 mins followed by ss...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D22269PubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50543142(CHEMBL4641633)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at TLR7 in human whole blood assessed as inhibition of DOTAP-ssRNA40 induced IFNalpha production preincubated for 30 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D22269PubMed
TargetToll-like receptor 7(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50543142(CHEMBL4641633)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Antagonist activity at TLR7 in mouse whole blood assessed as inhibition of DOTAP-ssRNA40 induced IFNalpha production preincubated for 30 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D22269PubMed