null
SMILES F[C@H]1CNCC[C@@H]1n1cc2cc(cc(c2n1)C(F)(F)F)-c1ccc(=O)n2CCCc12
InChI Key InChIKey=WLDNDKUPNXWOSV-WMZOPIPTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50543142
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 0.620nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of DOTAP-ssRNA40 induced IFNalpha production preincubated for 30 mins followed by ss...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at TLR7 in human whole blood assessed as inhibition of DOTAP-ssRNA40 induced IFNalpha production preincubated for 30 mins followe...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Mus musculus)
Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Antagonist activity at TLR7 in mouse whole blood assessed as inhibition of DOTAP-ssRNA40 induced IFNalpha production preincubated for 30 mins followe...More data for this Ligand-Target Pair