null
SMILES CN[C@@H]1CC2OC([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13
InChI Key InChIKey=YISMQBFJYDFMAL-AESIHLKFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 139540
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 0.550nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Temple University—Of The Commonwealth System Of Higher Education
US Patent
Affinity DataIC50: 0.196nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair