null

SMILES CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C(=O)c1cnc(cn1)N1CCCCC1

InChI Key InChIKey=XDJGNPSZQSWJCV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 139694   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Pfizer Limited

US Patent
LigandPNGBDBM139694(US8895544, 4)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:JAK3 enzyme (Invitrogen) stock solution is made up at 4.1 uM in sterile water. JAK3 enzyme stock is diluted to 2 nM in assay buffer (10 mM HEPES free...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QNMUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Pfizer Limited

US Patent
LigandPNGBDBM139694(US8895544, 4)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of GST tagged human recombinant JAK3 catalytic domain expressed in baculovirus using peptide substrate preincubated for 60 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HDZPubMed