null
SMILES CN1CCN(CC1)c1cc(Nc2cc(C)n[nH]2)nc(Sc2ccc(NC(=O)C3CC3)cc2)n1
InChI Key InChIKey=GCIKSSRWRFVXBI-UHFFFAOYSA-N
PDB links: 11 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 13534
Affinity DataKi: 80nM ΔG°: -9.58kcal/molepH: 7.5 T: 2°CAssay Description:The kinase activity was determined by incubation of enzyme and its substrate, and test compound, in the presence ATP/[gamma-32P] ATP. After incubatio...More data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of LckChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair