null
SMILES O=c1nc2n(-c3ccccc3)c3ccccc3cc2c(=O)[nH]1
InChI Key InChIKey=BBWFTVFLVHVBCD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50438882
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
University of Manchester
Curated by ChEMBL
University of Manchester
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TDP2 (unknown origin) using 5'-Y-TCCGTTGAAGCCTGCTTT-3' as substrate after 60 minsMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
University of Manchester
Curated by ChEMBL
University of Manchester
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrate after 60 minsMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
University of Manchester
Curated by ChEMBL
University of Manchester
Curated by ChEMBL
Affinity DataIC50: 7.10E+4nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+5nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
University of Manchester
Curated by ChEMBL
University of Manchester
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair