null
SMILES NC(N)=S
InChI Key InChIKey=UMGDCJDMYOKAJW-UHFFFAOYSA-N
PDB links: 5 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 30 hits for monomerid = 50229993
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataKi: 1.96E+4nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataKi: 2.00E+4nM IC50: 2.10E+4nMAssay Description:Reaction mixture consisting of 25 µL of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 µL of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysi...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataKi: 2.00E+4nM IC50: 2.10E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataKi: 2.30E+4nMAssay Description:Inhibition of Canavalia ensiformis (jack bean) urease assessed as release of ammonia after 30 min by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMpH: 6.8 T: 2°CAssay Description:Reaction mixtures comprising 25 μL of enzyme (jack bean urease) solution and 55 μL of buffer containing 100 mM urea were incubated with 5 &...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:The synthesized compounds (4a-e, 5a-e) were tested for their in vitro urease inhibition activities at 0.2 mM concentration against jack bean urease. ...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Reaction mixtures comprising 25 μL of enzyme (jack bean urease) solution and 55 μL of buffers containing 100 mM urea were incubated with 5 ...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMpH: 6.8 T: 2°CAssay Description:Mixture of 25 μL of urease enzyme (Jack bean) solution containing 1 unit of enzyme (1 unit = 0.02 mg of enzyme) was dissolved in phosphate buffe...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production incubated at 30 degC for 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Weatherburn assayMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of jack beans urease assessed as hydrolysis of urea into ammonia preincubated for 10 mins followed by urea addition measured after 10 mins...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as reduction in ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 6.83E+5nMAssay Description:Inhibition of Jack bean urease using urea as substrate assessed as production of ammonia after 15 minsMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 6.83E+5nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 minsMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Canavalia ensiformis (jack bean) urease assessed as inhibition of ammonia production after 15 min by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Canavalia ensiformis (jack bean) urease using urea as substrate after 15 min by indophenol-based spectrophotometric analysisMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 1.95E+4nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.09E+4nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
In DepthDetails
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.11E+4nMAssay Description:In vitro inhibition assay using jack bean urease.More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
COMSATS Institute of Information Technology
Curated by ChEMBL
COMSATS Institute of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition assay using urease from jack bean.More data for this Ligand-Target Pair