null

SMILES COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC

InChI Key InChIKey=YHUIUSRCUKUUQA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4621   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM4621(Anilinoquinazoline deriv. 4 | CHEMBL150315 | N-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47MBMPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM4621(Anilinoquinazoline deriv. 4 | CHEMBL150315 | N-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against VEGFR2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V2XPubMed