null
SMILES OC(=O)c1ccc(cc1)-c1cc2cccnc2c(n1)-c1ccc2nonc2c1
InChI Key InChIKey=IALXIRPKVRUJQO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50108504
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Induction of SQSTM1-dependent intracellular redistribution of GFP-tagged PDE4A4 assessed as maximal accretion of enzyme into fociMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of full-length PDE4A4 using cAMP as substrate by two-step radiochemical assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataIC50: 602nMAssay Description:Inhibition of PDE4A (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataIC50: 602nMAssay Description:Inhibition of human Phosphodiesterase 4A from peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataIC50: 602nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
In DepthDetails