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SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34

InChI Key InChIKey=WIYUZYBFCWCCQJ-XEWUMVRVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 21864   

TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)copy SMILEScopy InChI
Affinity DataEC50:  0.110nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding at human recombinant Opioid receptor delta 1 transfected into CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945F9PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)copy SMILEScopy InChI
Affinity DataEC50:  4.30nMAssay Description:Stimulation of DAMGO binding in recombinant human Opioid receptor mu 1 transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945F9PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)copy SMILEScopy InChI
Affinity DataEC50:  5nMAssay Description:Stimulation of U-69,593 binding at human recombinant Opioid receptor kappa 1 transfected into CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945F9PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)copy SMILEScopy InChI
Affinity DataEC50:  4.30nMAssay Description:Effective concentration agonistic activity towards Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8NGDPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)copy SMILEScopy InChI
Affinity DataEC50:  0.110nMAssay Description:Agonistic activity towards Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8NGDPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)copy SMILEScopy InChI
Affinity DataEC50:  5nMAssay Description:Agonistic activity towards Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8NGDPubMed
TargetNociceptin receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)copy SMILEScopy InChI
Affinity DataEC50:  3.90nMAssay Description:Activity at NOP expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0H37PubMed