null
SMILES [H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)c1ccccc1)C(=O)OC)N2C
InChI Key InChIKey=ZPUCINDJVBIVPJ-LJISPDSOSA-N
PDB links: 7 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 22418
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 272nM EC50: 267nMAssay Description:Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataKi: 276nM ΔG°: -8.85kcal/mole EC50: 416nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University of Toronto
Curated by PDSP Ki Database
University of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 371nM ΔG°: -8.68kcal/mole EC50: 303nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataKi: 601nM EC50: 318nMAssay Description:Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataKi: 830nM EC50: 385nMAssay Description:Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataKi: 1.12E+3nM EC50: 835nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair