null
SMILES Fc1ccc(cc1Cl)C(=O)N1CCC(F)(CNCCOc2ccccc2)CC1
InChI Key InChIKey=DXWRIDGYFFSIIY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 433474
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 10nMAssay Description:Biased agonist activity at Gal4-VP16 transcription factor linked human 5-HT1A receptor expressed in human U2OS cells assessed as induction of beta-ar...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 8.10nMAssay Description:Biased agonist activity at human 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 0.794nMAssay Description:Biased agonist activity at human 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in ERK1/2 phosphorylation after 15 mins by Alp...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 41nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in calcium mobilization measured a...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 63nMAssay Description:Biased agonist activity at human 5-HT1A receptor stably expressed in CHO-K1 cells co-expressing Galpha16/GPCR assessed as increase in calcium mobiliz...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 8.10nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumu...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 0.794nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in ERK1/2 phosphorylation levels i...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
NEUROLIXIS; UNIVERSITE JAGELLONE
US Patent
Affinity DataEC50: 10nMAssay Description:Biased agonist activity at Gal4-VP16 transcription factor linked human 5-HT1A receptor expressed in human U2OS cells assessed as stimulation of beta-...More data for this Ligand-Target Pair