null

SMILES Fc1ccc(cc1Cl)C(=O)N1CCC(F)(CNCCOc2cnccn2)CC1

InChI Key InChIKey=PCQQITDIAVWGLB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 433515   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM433515(US10562853, Compound 36)copy SMILEScopy InChI
Affinity DataEC50:  4.90nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in ERK1/2 phosphorylation levels i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T9HPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM433515(US10562853, Compound 36)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T9HPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM433515(US10562853, Compound 36)copy SMILEScopy InChI
Affinity DataEC50:  25nMAssay Description:Biased agonist activity at Gal4-VP16 transcription factor linked human 5-HT1A receptor expressed in human U2OS cells assessed as stimulation of beta-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T9HPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM433515(US10562853, Compound 36)copy SMILEScopy InChI
Affinity DataEC50:  29nMAssay Description:Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as increase in calcium mobilization measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T9HPubMed