null

SMILES COc1nc2cc(Cl)c(OC)cc2n1CCNC(C)=O

InChI Key InChIKey=BVSLRGAPRGQWNC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 463447   

TargetMelatonin receptor type 1A(Homo sapiens (Human))TBA
LigandPNGBDBM463447(US10781182, Compound IA2-143 | US11091445, Compoun...)copy SMILEScopy InChI
Affinity DataEC50:  0.0630nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CZJPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))TBA
LigandPNGBDBM463447(US10781182, Compound IA2-143 | US11091445, Compoun...)copy SMILEScopy InChI
Affinity DataEC50:  0.860nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CZJPubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))TBA
LigandPNGBDBM463447(US10781182, Compound IA2-143 | US11091445, Compoun...)copy SMILEScopy InChI
Affinity DataEC50:  0.25nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in cAMP levels incubated at 28 degreeC by cellular dielectric spec...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CZJPubMed