null

SMILES C[C@@](O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=LKJPYSCBVHEWIU-QGZVFWFLSA-N

PDB links: 1 PDB ID matches this monomer. 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18692   

TargetBile salt export pump(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM18692((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-f...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP488MPubMed
TargetAndrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM18692((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-f...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of androgen receptor in human LNCAP cells after 1 day by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZMRPubMed
TargetAndrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM18692((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-f...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human androgen receptor expressed in human CV1 cells assessed as inhibition of receptor-mediated transactivation by MMTV-lucif...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HW5PubMed