null
SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
InChI Key InChIKey=ASXGJMSKWNBENU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 39 hits for monomerid = 21393
Affinity DataIC50: 4nMAssay Description:The compound was tested in vitro for inhibitory activity against 5-HT1A receptor in rats, using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against dopamine receptor in rats using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptam...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:In vitro binding affinity measured on serotonin 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of forskolin-activated adenylate cyclase (cAMP) activity at 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Compound was evaluated for the binding affinity towards Dopamine receptor D2 using [3H]-raclopride radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Compound was evaluated for binding affinity on Dopamine receptor D1 using calf striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Cooperation Pharmaceutique Fran�aise
Curated by ChEMBL
Cooperation Pharmaceutique Fran�aise
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration of the compound against binding of Dopamine receptor D2 by displacement of [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor using receptor binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataIC50: 0.530nMAssay Description:Displacement of [3H]8-OHDPAT from human recombinant 5-HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro binding activity against dopamine D1 receptor from homogenized rat brain, using [3H]SCH-23390 as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:In vitro binding activity against 5-hydroxytryptamine 1A receptor receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.76E+3nMAssay Description:In vitro binding activity against Dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity towards dopamine receptor D1 in calf striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Binding affinity against serotonin 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Binding affinity to rat Dopamine receptor D2 expressed in CHO cells was determined using [125 I ] iodosulpride as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University of Camerino
Curated by ChEMBL
University of Camerino
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 2A receptor was evaluated using [3H]- ketanserin as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 1A receptor was evaluated using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Binding affinity towards rat Dopamine receptor D2 was evaluated using [3H]- spiroperidol as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against norepinephrine transporter (NET) by displacement of [3H]nisoxetine in male wistar ratsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University of Camerino
Curated by ChEMBL
University of Camerino
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against dopamine transporter (DAT) by displacement of [3H]WIN-35428 in male wistar ratsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
FAES FARMA S A
Curated by ChEMBL
FAES FARMA S A
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against serotonin transporter (SERT) by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]-ketanserinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Binding affinity against 5-HT1B receptor in rat frontal cortex using [3H]-5-HT in presence of 0.1 uM [3H]-8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Apparent inhibition constant (Ki) for cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataIC50: 0.530nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Alberta
Curated by PDSP Ki Database
University of Alberta
Curated by PDSP Ki Database
Affinity DataIC50: 0.280nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair