null
SMILES CN1CCN(CC1)C(=O)c1cc2cc(Cl)ccc2[nH]1
InChI Key InChIKey=HUQJRYMLJBBEDO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 22566
Affinity DataIC50: 40nMAssay Description:Inhibition of histamine H4 receptor-mediated chemotaxis in mouse bone marrow cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at H4R in human eosinophils assessed as inhibition of imetit-induced shape change by GAFS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at H4R in human eosinophils assessed as inhibition of histamine-induced actin polymerisationMore data for this Ligand-Target Pair
Affinity DataIC50: 221nMAssay Description:Antagonist activity at H4R in human eosinophils assessed as inhibition of histamine-induced CD11b upregulationMore data for this Ligand-Target Pair
Affinity DataIC50: 199nMAssay Description:Antagonist activity at H4R in human eosinophils assessed as inhibition of histamine-induced shape change by GAFS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Antagonist actiivty at human H4R expressed in human U2OS cells assessed as inhibition of [35S]GTPgammaS binding after 30 mins by scintillation proxim...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at recombinant human H4 receptor expressed in CHOK1 cells co-expressing Galpha16/aequorin assessed as inhibition of histamine-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of histamine H4 receptor-mediated chemotaxis in human eosinophilsMore data for this Ligand-Target Pair