null

SMILES COC(=O)[C@@H]1C2CC[C@H](C[C@@H]1c1ccc(I)cc1)N2C

InChI Key InChIKey=SIIICDNNMDMWCI-VOFREWHGSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50006774   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 4.21nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0TGBPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736RJCPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]WIN-35428l binding to Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736RJCPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0TGBPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Binding affinity towards serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66K4VPubMed
TargetTransporter(Rattus norvegicus)
Yale School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]mazindol binding to Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736RJCPubMed