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SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI Key InChIKey=OLNJKAXRBXUBTB-JYJNAYRXSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50286441   

TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of Cysteine protease falcipain-2 in Plasmodium falciparum HB3-leuR1 mutant infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q8WPubMed
TargetCysteine proteinase falcipain 3(Plasmodium falciparum)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of Cysteine protease falcipain-3 in Plasmodium falciparum HB3 infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q8WPubMed
TargetCysteine proteinase falcipain 3(Plasmodium falciparum)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of Cysteine protease falcipain-3 in Plasmodium falciparum HB3-leuR1 mutant infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q8WPubMed
TargetProthrombin(Bos taurus (Bovine))
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of thrombin with benzoyl-Phe-Val-arginine- p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24F1RCRPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of kallikrein with benzoyl-L-arginine ethyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24F1RCRPubMed
TargetSerine protease 1(Bos taurus (bovine))
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of trypsin with benzoyl-L-arginine ethyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24F1RCRPubMed
TargetPlasminogen(Bos taurus)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of plasmin with Val-L-Leu-L-lysine-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24F1RCRPubMed
TargetCathepsin B(Bos taurus (bovine))
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24F1RCRPubMed
TargetCathepsin B(Homo sapiens (Human))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33CXPubMed
TargetProcathepsin L(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human cathepsin L.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33CXPubMed
TargetCysteine protease(Leishmania donovani)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Leishmania donovani cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27W35PubMed
TargetCathepsin B(Homo sapiens (Human))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of cathepsin B by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26974HMPubMed
TargetPlasminogen(Homo sapiens (Human))
Medical University of Bialystok

LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320J8PubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of Cysteine protease falcipain-2 in Plasmodium falciparum HB3 infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2Q8WPubMed
TargetProcathepsin L(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Compound was measured for inhibition of collagenolytic of human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33CXPubMed
TargetTrypsin(Sus scrofa)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of pig pancreas trypsin type IX-SMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N0185FPubMed
TargetTrypsin(Sus scrofa)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of pig pancreas trypsin type IX-S using Boc-Gln-Ala-Arg-MCA substrate by 7-amino-4-methylcoumarin release based spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N0185FPubMed