null
SMILES N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O
InChI Key InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N
PDB links: 26 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50301375
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
TargetProliferating cell nuclear antigen(Homo sapiens (Human))
St. Jude Children's Research Hospital
Curated by ChEMBL
St. Jude Children's Research Hospital
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarizat...More data for this Ligand-Target Pair
Affinity DataIC50: 7.86E+3nMAssay Description:Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
College of Pharmacy, Dongguk University , Goyang 10326, Korea.
Curated by ChEMBL
College of Pharmacy, Dongguk University , Goyang 10326, Korea.
Curated by ChEMBL
Affinity DataIC50: 4.36E+4nMAssay Description:Inhibition of MDH2 (unknown origin)More data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 4C1(Homo sapiens)
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of Triiodothyronine uptake in OATP4C1-expressing MDCK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair