null
SMILES [H][C@@]12C[C@]([H])(C(=C/OC)\C(=O)OC)[C@]([H])(CC)CN1CC[C@]21Nc2cccc(OC)c2C1=O
InChI Key InChIKey=BAEJBRCYKACTAA-WGUOAFTMSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50474150
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.282nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of delta opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School of Pharmacy
Curated by ChEMBL
Temple University School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of DAMGO-induced beta-arrestin-2 recruitment at mu opioid receptor-1 (unknown origin) expressed in CHO cells preincubated for 30 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Antagonist activity at mouse delta opioid receptor-1 expressed in CHO cell membranes assessed as inhibition of DPDPE-induced [35S]GTPgammaS binding i...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Antagonist activity at mouse kappa opioid receptor-1 expressed in CHO cell membranes assessed as inhibition of U50,488H-induced [35S]GTPgammaS bindin...More data for this Ligand-Target Pair