null
SMILES CC(C)(C)c1cc(NC(=O)CSc2nnnn2-c2ccccc2)n(n1)-c1ccccc1
InChI Key InChIKey=KZFPHKZQVCYHEZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50525709
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human TrkB transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of inactive recombinant human His-tagged TrkA expressed in baculovirus expression system preincubated for 20 mins followed by ATP/CSKtide ...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of activated recombinant human His-tagged TrkA expressed in baculovirus expression system preincubated for 20 mins followed by ATP/CSKtide...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of activated recombinant human His-tagged TrkB expressed in baculovirus expression system preincubated for 20 mins followed by ATP/SRCtide...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human His-tagged TrkA kinase domain (441-796 residues) expressed in baculovirus expression system incubated with enzyme/ATP...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant full length human TrkA transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of inactive recombinant human His-tagged TrkB expressed in baculovirus expression system preincubated for 20 mins followed by ATP/SRCtide ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TrkA in rat PC12 cells assessed as reduction in beta-NGF-induced neurite outgrowth incubated for 7 days by live cell imaging analysisMore data for this Ligand-Target Pair