null

SMILES COc1nnc2ccc(nn12)N1CCC(CC1)c1ccc(OCCN2[C@H](C)CN(C)C(=O)[C@H]2C)cc1

InChI Key InChIKey=BZVORIOTWGQFRM-RTBURBONSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50534815   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50534815(CHEMBL4457035)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of BRD4 in human MM1S cells assessed as down regulation of c-Myc incubated for 16 hrs by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2697721PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50534815(CHEMBL4457035)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD4 in human MCF7 cells assessed as down regulation of ERalpha after 18 to 24 hrs by Hoechst staining based cellomics arrayscan analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2697721PubMed