null
SMILES CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
InChI Key InChIKey=QJJXYPPXXYFBGM-LFZNUXCKSA-N
PDB links: 31 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50030448
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Guilford Pharmaceuticals, Inc.
Curated by ChEMBL
Guilford Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKd: 0.200nMAssay Description:The compound was evaluated for its affinity to the binding domain of immunophilin FK506 binding protein 12More data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to protein phosphatase, calcineurin (CN) was determinedMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Guilford Pharmaceuticals, Inc.
Curated by ChEMBL
Guilford Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKd: 0.200nMAssay Description:Binding affinity to FK506 binding protein 12 was determinedMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Homo sapiens (Human))
Max Planck Institute of Psychiatry
Curated by ChEMBL
Max Planck Institute of Psychiatry
Curated by ChEMBL
In DepthDetails
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Guilford Pharmaceuticals, Inc.
Curated by ChEMBL
Guilford Pharmaceuticals, Inc.
Curated by ChEMBL
TargetPeptidyl-prolyl cis-trans isomerase FKBP1B(Homo sapiens (Human))
Janssen Pharmaceutical Research and Development, LLC
Curated by ChEMBL
Janssen Pharmaceutical Research and Development, LLC
Curated by ChEMBL
Affinity DataKd: 0.400nMAssay Description:Binding affinity to FKBP12 (unknown origin) by NMR analysisMore data for this Ligand-Target Pair