null
SMILES OC(=O)c1cccnc1Nc1cccc(c1)C(F)(F)F
InChI Key InChIKey=JZFPYUNJRRFVQU-UHFFFAOYSA-N
PDB links: 4 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 85507
Affinity DataKd: 260nMAssay Description:Binding affinity to TTR (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 592nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
Affinity DataKd: 2.80E+4nMAssay Description:Binding affinity to human His-tagged TEAD4 YBD (217 to 434 residues) expressed in Escherichia coli BL21(DE3) after 30 mins by ITC assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.80E+4nMAssay Description:Binding affinity to N-terminal His6-tagged human TEAD4 YAP binding domain (217 to 434 residues) expressed in Escherichia coli C43 (DE3) cells by ITC ...More data for this Ligand-Target Pair
Affinity DataKd: 2.80E+4nMAssay Description:Binding affinity to His-tagged TEAD4 YPD domain (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titrati...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 85507
ITC DataΔG°: -8.48kcal/mole −TΔS°: 9.54kcal/mole ΔH°: -18.1kcal/mole logk: 1.66E+6
pH: 7.5 T: 25.00°C
pH: 7.5 T: 25.00°C