null

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO

InChI Key InChIKey=JIRXORZYIXSWOB-UHFFFAOYSA-N

PDB links: 10 PDB IDs match this monomer. 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 13080   

TargetCollagenase 3(Homo sapiens (Human))
ProtEra s.r.l.

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N2WPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
ProtEra s.r.l.

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
ProtEra s.r.l.

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N2WPubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  132nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  133nM ΔG°:  -9.75kcal/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
ProtEra s.r.l.

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  174nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N2WPubMed
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute for Cell Therapy and Immunology IZI

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of human meprin beta expressed in baculovirus infected BTI-TN-5B1-4 insect cells using N-benzoyl-L-tyrosylp-aminobenzoic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5WH0PubMed
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute for Cell Therapy and Immunology IZI

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of recombinant human meprin beta expressed in baculovirus infected insect cells using N-benzoyl-L-tyrosyl-p-aminobenzoic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6V47PubMed
TargetMatrilysin(Homo sapiens (Human))
ProtEra s.r.l.

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N2WPubMed