null
SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO
InChI Key InChIKey=JIRXORZYIXSWOB-UHFFFAOYSA-N
PDB links: 10 PDB IDs match this monomer. 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 13080
Affinity DataKi: 3.10nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 132nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
Affinity DataKi: 133nM ΔG°: -9.75kcal/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute for Cell Therapy and Immunology IZI
Curated by ChEMBL
Fraunhofer Institute for Cell Therapy and Immunology IZI
Curated by ChEMBL
Affinity DataKi: 7.40E+3nMAssay Description:Inhibition of human meprin beta expressed in baculovirus infected BTI-TN-5B1-4 insect cells using N-benzoyl-L-tyrosylp-aminobenzoic acid as substrateMore data for this Ligand-Target Pair
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute for Cell Therapy and Immunology IZI
Curated by ChEMBL
Fraunhofer Institute for Cell Therapy and Immunology IZI
Curated by ChEMBL
Affinity DataKi: 7.40E+3nMAssay Description:Inhibition of recombinant human meprin beta expressed in baculovirus infected insect cells using N-benzoyl-L-tyrosyl-p-aminobenzoic acid as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair