null

SMILES CCCc1nc(C)c2n1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(CC)CC1

InChI Key InChIKey=SECKRCOLJRRGGV-UHFFFAOYSA-N

PDB links: 5 PDB IDs match this monomer. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14776   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

LigandBDBM14776(2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phen...)copy SMILEScopy InChI

Affinity DataKi:  1nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0N2HPubMedMMDB
PDB
3D Structure (crystal)

TargetGlycerophosphocholine phosphodiesterase GPCPD1(RAT)
Medical College of Georgia

Curated by PDSP K_i Database

LigandBDBM14776(2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phen...)copy SMILEScopy InChI

Affinity DataKi:  2.95nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9VX2PubMed