null
SMILES O=C1C(=O)c2ccccc2-c2ccccc12
InChI Key InChIKey=YYVYAPXYZVYDHN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 22857
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children's Research Hospital
Curated by ChEMBL
St. Jude Children's Research Hospital
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of human CE1 using o-NPA as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children's Research Hospital
Curated by ChEMBL
St. Jude Children's Research Hospital
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Inhibition of human iCE using o-NPA as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 52nM ΔG°: -9.93kcal/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair