null

SMILES OC(=O)[C@@H]1CCCN1

InChI Key InChIKey=ONIBWKKTOPOVIA-BYPYZUCNSA-N

PDB links: 59 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50000100   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
E£tv£s Lor£nd University

Curated by ChEMBL

LigandBDBM50000100((-)-(S)-proline | (-)-2-pyrrolidinecarboxylic acid...)copy SMILEScopy InChI

Affinity DataKi:  8.60E+4nMAssay Description:Inhibition of ACE (unknown origin) assessed as 3-Hydroxybutyril-glycil-glycil-glycine conversion to 3-hydroxybutyric acid after 60 mins by WST assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankMCE
KEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7SGGPubMedPDB
3D Structure (crystal)

TargetProton-coupled amino acid transporter 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

LigandBDBM50000100((-)-(S)-proline | (-)-2-pyrrolidinecarboxylic acid...)copy SMILEScopy InChI

Affinity DataKi:  1.60E+6nMAssay Description:Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankMCE
KEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ882DPubMed