null
SMILES COc1cccc(c1)-c1ccc(Cc2cc(C)cc(=O)n2O)cc1
InChI Key InChIKey=HDSJLXOOGNLQBT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50029491
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine
Curated by ChEMBL
Baylor College of Medicine
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Inhibition of human IDH1 R132H mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine
Curated by ChEMBL
Baylor College of Medicine
Curated by ChEMBL
Affinity DataKi: 620nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine
Curated by ChEMBL
Baylor College of Medicine
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of wild type human IDH1 expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair