null
SMILES CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1
InChI Key InChIKey=YKPYIPVDTNNYCN-INIZCTEOSA-N
PDB links: 3 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50082556
Affinity DataKi: 0.0380nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0380nMAssay Description:Inhibition of collagenase (Matrix metalloprotease-13)More data for this Ligand-Target Pair
In DepthDetails
Affinity DataKi: 0.0500nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: 0.0830nMAssay Description:Inhibition of gelatinase-A (Matrix metalloprotease-2)More data for this Ligand-Target Pair
Affinity DataKi: 0.0830nMAssay Description:Inhibition of matrix metalloprotease-2 (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataKi: 0.270nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Inhibition of collagenase-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1).Checked by AuthorMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
Affinity DataKi: 54nMAssay Description:Inhibition of matrilysin (Matrix metalloprotease-7)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
In DepthDetails