null

SMILES COc1cc(C[C@@H](C)N)c(OC)cc1I

InChI Key InChIKey=BGMZUEKZENQUJY-SSDOTTSWSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50133231   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research, Ltd.

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:In vitro inhibitory constant against [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320C1PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Alcon Research, Ltd.

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  0.650nMAssay Description:Inhibitory constant against cloned human 5-hydroxytryptamine 2A receptor using with [125I]- DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320C1PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Alcon Research, Ltd.

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  0.650nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5ZQWPubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))TBA
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT2B receptor expressed in CHO cells by radioligand completion assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9VBRPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Alcon Research, Ltd.

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5ZQWPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Alcon Research, Ltd.

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibitory constant against cloned human 5-hydroxytryptamine 2C receptor using with [125I]- DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320C1PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Alcon Research, Ltd.

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT2A receptor expressed in HEK cells by radioligand completion assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9VBRPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]ketanserin from rat prefrontal cortex 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KP84CDPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BS7PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))TBA
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5ZQWPubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))TBA
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibitory constant against cloned human 5-hydroxytryptamine 2B receptor using with [125I]- DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320C1PubMed
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  2.29E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1 receptor of rat prefrontal cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KP84CDPubMed
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  2.29E+3nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BS7PubMed
LigandPNGBDBM50133231((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BS7PubMed