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SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI Key InChIKey=OLNJKAXRBXUBTB-JYJNAYRXSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50286441   

TargetCathepsin B(Capra hircus (Goat))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Competitive inhibition of goat brain cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319XDVPubMed
TargetCathepsin B(Homo sapiens (Human))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319XDVPubMed
TargetCathepsin B(Homo sapiens (Human))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XQHPubMed
TargetSerine protease 1(Homo sapiens (Human))
Medical University of Bialystok

LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  8nMpH: 7.5Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3XTKPubMed
TargetPlasminogen(Homo sapiens (Human))
Medical University of Bialystok

LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3XTKPubMed
TargetCathepsin B(Capra hircus (Goat))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Competitive inhibition of goat brain cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XQHPubMed
TargetSerine protease hepsin(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Inhibition of recombinant hepsin (unknown origin) using Boc-QAR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4DV8PubMed
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  188nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4DV8PubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  696nMAssay Description:Inhibition of matriptase (unknown origin) using Boc-QAR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4DV8PubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B02PDPubMed
TargetTransmembrane protease serine 6(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B02PDPubMed
TargetTransmembrane protease serine 6(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B02PDPubMed
TargetPro-cathepsin H(Homo sapiens (Human))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of human liver cathepsin HMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319XDVPubMed
TargetPro-cathepsin H(Homo sapiens (Human))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of human liver cathepsin HMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XQHPubMed