null

SMILES OC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1

InChI Key InChIKey=UOWZUVNAGUAEQC-UHFFFAOYSA-N

PDB links: 13 PDB IDs match this monomer. 2 PDB IDs contain this monomer as substructures. 2 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 18862   

TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of bound [125I]L-T3 rat plasma membrane 3,5,3'' L-triiodothyronine receptorMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 3.48E+4nMAssay Description:Transcriptional activity at human androgen receptor BF3 site stably transfected in eGFP-expressing human LNCAP cells after 5 days by fluorometric ana...More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University of Insubria

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.0479nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University of Insubria

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.0407nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Universidade de S£o Paulo

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.141nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
TargetPutative hydrolase(Pseudomonas aeruginosa (strain UCBPP-PA14))
AstraZeneca

LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f...More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Universidade de S£o Paulo

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University of Insubria

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.0480nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair