null
SMILES CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
InChI Key InChIKey=WUPUZEMRHDROEO-UHFFFAOYSA-N
PDB links: 2 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 31826
TargetEpidermal growth factor receptor [668-1210](Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society
Chemical Genomics Centre of the Max Planck Society
Affinity DataIC50: 0.430nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society
Chemical Genomics Centre of the Max Planck Society
Affinity DataIC50: 360nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre of the Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of wild type EGFR by HTRF assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre of the Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 2.62nMAssay Description:Inhibition of recombinant EGFR by ELISAMore data for this Ligand-Target Pair