null

SMILES CN1CCN(CC1)c1nc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc2n1

InChI Key InChIKey=OAVGBZOFDPFGPJ-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 33971   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis

LigandPNGBDBM33971(AEB071 | Sotrastaurin | med.21724, Compound 190)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis

LigandPNGBDBM33971(AEB071 | Sotrastaurin | med.21724, Compound 190)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PKCalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis

LigandPNGBDBM33971(AEB071 | Sotrastaurin | med.21724, Compound 190)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PKCalpha (unknown origin) after 60 mins in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis

LigandPNGBDBM33971(AEB071 | Sotrastaurin | med.21724, Compound 190)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMMore data for this Ligand-Target Pair