null
SMILES OC1(N2CCCN=C2c2ccccc12)c1ccc2OCOc2c1
InChI Key InChIKey=WCGSHYCCXQCRIA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50118266
Affinity DataKi: 2.55nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 8.80nMAssay Description:Ability to displace [125I]- RTI-55 binding at the Norepinephrine transporter site on HEK cells expressing cDNA for the human transporter (hNET)More data for this Ligand-Target Pair
Affinity DataKi: 25.6nMAssay Description:Displacement of [125I]- RTI-55 from Serotonin transporter expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.09nMAssay Description:Inhibition of [3H]WIN-35428 radioligand binding to the Dopamine Transporter in guinea pig striatal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.21nMAssay Description:Ability to block the uptake of 5-HT at the Dopamine transporter of HEK cells expressing cDNA for the human transporter (hDAT)More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of 5-HT uptake in HEK cells expressing human serotonin transporter (hSERT)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 0.620nMAssay Description:Inhibition of NE uptake in HEK cells expressing human noradrenaline transporter (hNET)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 1.94nMAssay Description:Ability to displace [3H]WIN-35428 from Dopamine Transporter of rat striatal membraneMore data for this Ligand-Target Pair