null

SMILES Cc1ccccc1-n1c(Cn2nc(C#CCO)c3c(N)ncnc23)nc2cccc(C)c2c1=O

InChI Key InChIKey=GJBJSDBBRWPDBE-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323730   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

LigandBDBM50323730(2-((4-amino-3-(3-hydroxyprop-1-ynyl)-1H-pyrazolo[3...)copy SMILEScopy InChI

Affinity DataIC50: 7nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0B47PubMedMMDB
PDB
3D Structure (crystal)

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

LigandBDBM50323730(2-((4-amino-3-(3-hydroxyprop-1-ynyl)-1H-pyrazolo[3...)copy SMILEScopy InChI

Affinity DataIC50: 7nMAssay Description:Inhibition of p110deltaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP82CKPubMedMMDB
PDB
3D Structure (crystal)