null

SMILES CCc1ccc(cc1)-c1ccc2N(C)S(=O)(=O)c3c[nH]nc3-c2c1

InChI Key InChIKey=ISXAVIPPPMJTPN-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50430289   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FLAG-tagged unphosphorylated full length FAK expressed in baculovirus expression system incubated for 5 mins prior to 1000 uM of ...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 5 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 1000 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 1000 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human FAK using [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human FLAG-tagged unphosphorylated full length FAK expressed in baculovirus expression system incubated for 60 mins prior to 0.5 uM of ...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human FLAG-tagged unphosphorylated full length FAK expressed in baculovirus expression system incubated for 5 mins prior to 0.5 uM ATP ...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human GST-tagged phosphorylated full length FAK incubated for 60 mins prior to 1000 uM of ATP addition by HTRF analysisMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human GST-tagged phosphorylated full length FAK incubated for 5 mins prior to 1000 uM of ATP addition by HTRF analysisMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of human GST-tagged phosphorylated full length FAK incubated for 60 mins prior to 0.5 uM of ATP addition by HTRF analysisMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human GST-tagged phosphorylated full length FAK incubated for 5 mins prior to 0.5 uM of ATP addition by HTRF analysisMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:ATP-noncompetitive inhibition of human unphosphorylated FAK kinase domain (411 to 686) using Poly-(GT)-biotin as substrate incubated for 60 mins prio...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:ATP-noncompetitive inhibition of human unphosphorylated FAK kinase domain (411 to 686) using Poly-(GT)-biotin as substrate incubated for 5 mins prior...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:ATP-noncompetitive inhibition of human unphosphorylated FAK kinase domain (411 to 686) using Poly-(GT)-biotin as substrate incubated for 60 mins prio...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:ATP-noncompetitive inhibition of human unphosphorylated FAK kinase domain (411 to 686) using Poly-(GT)-biotin as substrate incubated for 5 mins prior...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human FLAG-tagged unphosphorylated full length FAK expressed in baculovirus expression system incubated for 60 mins prior to 1000 uM of...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair