null
SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 35 hits for monomerid = 50585046
Affinity DataIC50: 690nMAssay Description:Inhibition of SGK (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Affinity DataIC50: 5nMAssay Description:Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of MEK4 (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of YSK4 (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of RSK4 (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of FAK (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Inhibition of RSK2 (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Inhibition of MINK1 (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of JNK1 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of JNK2 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of FAK (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of RSK1 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of RSK2 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of RSK3 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of DYRK1A (unknown origin) at 1 uM by kinomescan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of DYRK1B (unknown origin) at 1 uM by kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
Affinity DataIC50: 3nMAssay Description:Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair