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SMILES C[C@H]1Cc2ccccc2N1C(=O)Cc1nc(cc(=O)[nH]1)N1CCOCC1

InChI Key

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 60631   

LigandPNGBDBM60631(BDBM50447096 | US9133168, 19b)copy SMILES
Affinity DataIC50: 60nMAssay Description:Inhibition of PI3Kbeta-mediated Akt phosphorylation at S473 in BRAF-V600E/PTEN-deficient human UACC62 cellsMore data for this Ligand-Target Pair
LigandPNGBDBM60631(BDBM50447096 | US9133168, 19b)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
LigandPNGBDBM60631(BDBM50447096 | US9133168, 19b)copy SMILES
Affinity DataIC50: 468nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kdelta expressed in baculovirus-infected sf9 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
LigandPNGBDBM60631(BDBM50447096 | US9133168, 19b)copy SMILES
Affinity DataIC50: 49nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair