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SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC

InChI Key InChIKey=PWEZBNRZEHPIIQ-JTQLQIEISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50007534   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi:  0.550nMAssay Description:Inhibition of [3H]raclopride binding to rat striatal dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5NS9PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi:  0.550nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58DRPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi:  6.10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Astra Läkemedel AB

Curated by PDSP Ki Database
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi:  1.02E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetD(1A) dopamine receptor(RAT)
Astra Läkemedel AB

Curated by PDSP Ki Database
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi:  1.05E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetAlpha-2C adrenergic receptor(RAT)
Astra Läkemedel AB

Curated by PDSP Ki Database
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi:  3.22E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Astra Läkemedel AB

Curated by PDSP Ki Database
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetD(1A) dopamine receptor(RAT)
Astra Läkemedel AB

Curated by PDSP Ki Database
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Astra Läkemedel AB

Curated by PDSP Ki Database
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Astra Läkemedel AB

Curated by PDSP Ki Database
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetHistamine H1 receptor(RAT)
Astra Läkemedel AB

Curated by PDSP Ki Database
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1Q7VPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:In vitro binding affinity at Dopamine receptor D2 in rat by displacing [3H]- spiperone from rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ2BHDPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]raclopride binding to rat striatal dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5NS9PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:In vivo inhibitory activity of the compound against dopamine (D2) receptor in rat caudate-putamen tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M07BCPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Tested in vitro for inhibition of [3H]spiperone binding to dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GZDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Mazandaran

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833T8SPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58DRPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:In vitro binding affinity at Dopamine receptor D2 in rat by displacing [3H]- spiperone from rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ2BHDPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre AB

Curated by ChEMBL
LigandPNGBDBM50007534(3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30MHPubMed