null

SMILES NC[C@@](O)(c1ccc(Cl)cc1)c1ccc(cc1)-c1cn[nH]c1

InChI Key InChIKey=IIRWNGPLJQXWFJ-KRWDZBQOSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50242733   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 402nMAssay Description:Inhibition of recombinant human full length His-tagged AKT2 expressed in baculovirus expression system using ser/thr 6 as substrate after 1 hr by FRE...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70J7FPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70J7FPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human His-tagged PKA catalytic domain (1 to 351 residues) expressed in Escherichia coli using Ser/Thr 7 as substrate after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70J7FPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human full length His-tagged AKT3 expressed in baculovirus expression system using ser/thr 6 as substrate after 1 hr by FRE...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70J7FPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In DepthDetails
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 402nMMore data for this Ligand-Target Pair
In DepthDetails
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 38nMMore data for this Ligand-Target Pair
In DepthDetails