null
SMILES CCOc1ccc(C[C@H]2NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)[C@@H](C)CC)[C@@H](C)O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O)cc1
InChI Key InChIKey=VWXRQYYUEIYXCZ-OBIMUBPZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50177595
TargetOxytocin receptor(Homo sapiens (Human))
GlaxoSmithKline Research and Development
Curated by ChEMBL
GlaxoSmithKline Research and Development
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Binding affinity to human oxytocin receptorMore data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
GlaxoSmithKline Research and Development
Curated by ChEMBL
GlaxoSmithKline Research and Development
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
GlaxoSmithKline Research and Development
Curated by ChEMBL
GlaxoSmithKline Research and Development
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Binding affinity to recombinant oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Displacement of [125I]OVTA antagonist from rat oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
GlaxoSmithKline Research and Development
Curated by ChEMBL
GlaxoSmithKline Research and Development
Curated by ChEMBL
Affinity DataKi: 397nMAssay Description:Binding affinity to oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonism of OT-induced response at OT receptor in rat uterine stripsMore data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
GlaxoSmithKline Research and Development
Curated by ChEMBL
GlaxoSmithKline Research and Development
Curated by ChEMBL
Affinity DataIC50: 372nMAssay Description:Compound was evaluated for OT receptor affinity by displacement of [3H]OT from binding sites in uterine tissue taken from nonlabor pregnant womenMore data for this Ligand-Target Pair
TargetOxytocin receptor(Homo sapiens (Human))
GlaxoSmithKline Research and Development
Curated by ChEMBL
GlaxoSmithKline Research and Development
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibitory activity against human Oxytocin induced intracellular Calcium mobilization in human Oxytocin receptor transfected HEK293-EBNA cellsMore data for this Ligand-Target Pair