null

SMILES COc1ccc(cc1)-c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=MCGDSOGUHLTADD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 19442   

TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois at Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 21.5nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ30Z9PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois at Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 66.3nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ30Z9PubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois at Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)p...)copy SMILEScopy InChI
Affinity DataEC50:  0.200nMAssay Description:Induction of estrogen receptor-alpha degradation in human MCF7 cells after 4 hrs by in-cell western assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H7QPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois at Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]-E2 from estrogen receptor-beta (unknown origin) by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H7QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois at Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Displacement of [3H]-E2 from estrogen receptor-alpha (unknown origin) by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0H7QPubMed