null

SMILES C(C1=CCCc2ncccc12)n1ccnc1

InChI Key InChIKey=DVAOHPCQHIOCSM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10025   

TargetAromatase(Homo sapiens (Human))
Universitat des Saarlandes

LigandPNGBDBM10025(5-(1H-imidazol-1-ylmethyl)-7,8-dihydroquinoline | ...)copy SMILEScopy InChI
Affinity DataIC50: 170nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21VTHPubMed
TargetAromatase(Homo sapiens (Human))
Universitat des Saarlandes

LigandPNGBDBM10025(5-(1H-imidazol-1-ylmethyl)-7,8-dihydroquinoline | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4CF5PubMed
TargetAromatase(Homo sapiens (Human))
Universitat des Saarlandes

LigandPNGBDBM10025(5-(1H-imidazol-1-ylmethyl)-7,8-dihydroquinoline | ...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Universitat des Saarlandes

LigandPNGBDBM10025(5-(1H-imidazol-1-ylmethyl)-7,8-dihydroquinoline | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Thromboxane A2 synthase activity was assayed by measuring the fragmentation of prostaglandin H2 to form 12-hydroxy-5, 8,10-heptadecatrienoic acid and...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21VTHPubMed