null

SMILES C[C@@H]1COCCN1c1cc(nc(n1)-c1cncc2[nH]ccc12)C1(CC1)S(C)(=N)=O

InChI Key InChIKey=QCLXSDKJICKOCU-RNHBAAACSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103471   

TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM103471(BDBM50456371 | US8552004, 2.11)copy SMILEScopy InChI
Affinity DataIC50: 13.8nMAssay Description:ATM and ATR have distinct and overlapping responses to DNA damage. They must participate together and responses must be co-ordinated. Both pathways...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P0XN6US Patent
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM103471(BDBM50456371 | US8552004, 2.11)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM103471(BDBM50456371 | US8552004, 2.11)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant FLAG-tagged full length ATR expressed in mammalian cell line co-expressing human recombinant cMyc-tagged full length ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918G5PubMed